An Insight into the Global Problem of Gastrointestinal Helminth Infections amongst Livestock: Does Nanotechnology Provide an Alternative?

Helminth parasitic infections are a considerable constraint to the livestock industries worldwide. Nematode parasites cause major proportion of harm livestock. The caused accountable for severe economic losses in cattle, goat and sheep farming industries. Morbidity mortality due diseases increasing alarmingly. Also, their zoonotic influence on human health is considered significant. Anthelmintic drugs have been developed occasionally curb this disease prevent losses. But development resistance against these has put another flourishing industry. three main classes anthelmintics: benzimidazoles, macrocyclic lactones nicotinic agonists. With intensification resistance, various screening confirmatory tests speedy introduction newer At same time, designing launching novel anthelmintics time-consuming economically restrained. Phytochemicals attract much attention because pharmacotherapeutic potential, least toxic profile low environmental hazards. A lot work going plant-based anthelmintic throughout world. Plants possessing activity found efficacious gastrointestinal parasites. Nevertheless, herbal medicines drawbacks, which include poor efficacy absence target selectivity. These problems now being taken care with help nanotechnology. Nanoparticles improve drug’s effectiveness, enhance drug delivery, selectivity at specific sites. comprehensive literature survey was carried out via electronic searches Google Scholar, PubMed, MEDLINE, Science Direct, Scopus Cochrane Library databases based inclusion exclusion criteria; articles were selected review. review aims providing overview nanoparticles as therapeutic alternatives over conventional synthetic drugs. It also encompasses methods detection ways overcome menace. effectiveness organic inorganic helminthes discussed